منابع مشابه
Experimental Pharmacological Model of Diabetes Induction with Aloxan in Rat
An experimental pharmacological model of diabetes induced with aloxan in white, male and female Wistar rats was designed. A collectivity of 312 animals was used, with an initial mean weight of 225.1 ± 31.48 g-bw and basal mean glycaemia of 103.0 ± 34.22 mg/dL. Diabetes was induced by administering intraperitoneally a dose of 130 mg/kg-bw alloxan. Experimental results showed that, in the tested ...
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the aim of the present study was to evaluate the effect of ethanolic extract of murraya koenigii leaves (mkl) on blood glucose level and in prevention or management of diabetic neuropathy. in the present study the diabetic neuropathy was developed 9 weeks after single injection of streptozotocin (stz, 70 mg/kg i.v.) in rat. the treatment with mkl (300 and 500 mg/kg p.o.) was started after stabi...
متن کاملExperimental Studies on Diabetes
1. The injurious effects of excessive carbohydrate diet are demonstrable in partially depancreatized dogs, in the same manner as in human patients. With severe diabetes there is rapid progress of emaciation and weakness and early death. 2. With milder diabetes, there is frequently a transitional state following operation, when the fate depends on the diet. If the tolerance is spared for a time,...
متن کاملStudies on Experimental Diabetes
Experimental diabetes has been characterized as a metabolic state involving both overproduction and underutilization of glucose. Although these changes have been recognized for many years, the specific biochemical alterations resulting in increased hepatic glucose production have not been adequately described. The adrenal cortical steroids are known, however, to have an important role in the re...
متن کاملEnsete superbum ameliorates renal dysfunction in experimental diabetes mellitus
Objective(s):Hyperglycemia mediated oxidative stress plays a key role in the pathogenesis of diabetic complications like nephropathy. In the present study, we evaluated the effect of ethanolic extract of Ensete superbum seeds (ESSE) on renal dysfunction and oxidative stress in streptozotocin-induced diabetic rats. Materials and Methods:Glucose, HbA1c, total protein, albumin, renal function mar...
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ژورنال
عنوان ژورنال: Istanbul Bilim University Florence Nightingale Journal of Medicine
سال: 2015
ISSN: 2149-4401
DOI: 10.5606/fng.btd.2015.008